Now placing non-clinical evaluation units

Faster, safer needle alignment for CT-guided procedures. Without the capital cost.

IRIS is a single-use, skin-mounted needle guide that turns the angle you plan on CT into a physical reference at the skin. Improve targeting, cut confirmation scans, and shorten procedures, with no new equipment and no change to your workflow.

Request an evaluation unit Watch the introduction
33%
faster needle alignment1
53%
less radiation exposure1
Animation of IRIS on a patient's abdomen: the guide is aligned to the red CT gantry laser over the skin entry site, then its angle scale is raised and a biopsy needle is advanced through the center hub.
Aligned to the CT laserat the skin entry site
Single-useNo capital equipment

Illustrative rendering of IRIS in use.

Incubated at Vanderbilt University Medical Center
Designed by an interventional radiologist
Fits the standard CT workflow
Patent pending

The problem

CT-guided procedures are precise by design, but still aligned by eye.

Most CT-guided needle placement still depends on the operator carrying an angle from the screen to the patient by eye, then scanning to check, adjusting, and scanning again.

~2 million

CT-guided biopsies performed in the U.S. every year, plus aspirations, drain placements, ablations, and injections.

Every check scan adds dose

Each confirmation scan adds radiation exposure for the patient and for the clinicians at the table.

Rescans tie up the CT suite

Repositioning and rescanning extend procedure and sedation time, and limit how many patients a scanner can serve each day.

Small errors compound with depth

A few degrees off at the skin becomes millimeters off at the target, often next to structures you have to avoid. Complications are costly for everyone.

Preclinical results

Measured in the lab. Built for the CT suite.

In head-to-head testing against standard technique, IRIS shortened needle alignment and cut the radiation needed to confirm placement.

33%

Faster needle alignment

A calibrated angle reference at the skin means less trial and error between planning and placement.

53%

Reduction in radiation exposure

Getting the angle right sooner means fewer confirmation scans for patients and the care team.

1. IRIS Biopsy internal preclinical study, 2025, compared with standard technique. These are preclinical results; clinical performance has not been established.

How it works

Three steps. No new equipment.

IRIS works with the planning scan you already take. Measure the angle, match it on the device, and advance with confidence.

  1. Top view: IRIS sits on the skin over the entry mark, with its base along the red CT gantry laser line.

    Step 01

    Align IRIS at the skin entry site

    Place IRIS over the marked entry site with its base along the CT gantry laser, so the guide sits in the same plane as your planning slice.

  2. Axial CT planning slice showing a trajectory from the skin entry point to the target at 49 degrees and 9.2 centimeters deep.

    Step 02

    Identify the entry angle and depth

    On the planning scan, measure the angle of approach and the distance from skin to lesion. These are the same measurements you take today.

  3. Cross-section showing the needle passing through the IRIS hub along the 49 degree mark and advancing to the lesion at the measured depth.

    Step 03

    Advance at the calculated angle

    Set the needle against the matching mark on the IRIS scale and advance to the measured depth, with fewer adjustments and fewer check scans.

Single-useDisposable, one per procedure
Skin-mountedSits at the entry site, in plane
Calibrated scaleRead the angle like a protractor
Nothing to installNo software, power, or capital
Designed for CT-guided Biopsy Aspiration Drain placement Ablation Therapeutic injection

Who benefits

Value at every level of care, from the needle to the network.

IRIS is a simple device with an outsized effect. Here's what it means for each person who touches a CT-guided procedure.

Clinicians 33% faster alignment1

Plan the angle. Hit the angle.

  • A calibrated, physical reference replaces estimating the angle by eye.
  • Fewer repositionings and check scans between planning and placement.
  • Builds confidence for trainees and standardizes technique across operators.
  • No software, setup, or new hardware to learn.
Patients 53% less radiation1

Less dose. Less time on the table.

  • Fewer confirmation scans means lower radiation exposure.
  • Fewer needle adjustments, designed to reduce the risk of complications.
  • Shorter procedures can mean less time under sedation.
Practices $0 capital equipment

More cases through the same CT suite.

  • Faster setup and alignment free up scanner time for more procedures per day.
  • No capital purchase, maintenance, or service contract.
  • Drops into existing procedure kits and workflows without retraining staff.
Health systems Per-procedure cost

Precision without a capital request.

  • A single-use supply item, with no capital committee and nothing to install.
  • Supports radiation-safety (ALARA) goals for patients and staff.
  • Consistent technique across sites, operators, and training programs.
  • Better scanner utilization and fewer costly complications.

Why IRIS

The precision of guidance. The simplicity of a disposable.

Freehand technique costs nothing up front but depends on experience. Navigation and robotic systems add precision at a significant price. IRIS sits in between.

Freehand Navigation & robotics IRIS
Capital equipment None Significant purchase None
Setup None Dedicated setup and registration Place on skin and align to laser
Angle reference Visual estimate Software-guided Calibrated physical scale
Confirmation scans Frequent Reduced Reduced: 53% less radiation in testing1
Learning curve Experience-dependent Vendor training program Intuitive, reads like a protractor
Footprint in the suite None Console or cart Fits in a procedure kit

Introduction

See IRIS in action.

IRIS device introduction Incubated at Vanderbilt University Medical Center

Team

Founded at Vanderbilt. Built for every CT suite.

Dr. Dann Martin

Dr. Dann Martin

Founder & CEO

Assistant Professor of Neuroradiology at Vanderbilt University and an interventional radiologist with over a decade of CT-guided procedure experience. Dann trained at Johns Hopkins, Tufts, Lahey, and Stanford and is passionate about simplifying biopsy workflows to improve patient outcomes.

LinkedIn
Jonathan Sadlowe

Jonathan Sadlowe, MBA

Co-Founder & COO

Co-Founder and COO of IRIS and Entrepreneur-in-Residence at Vanderbilt University Medical Center. Jon was previously CMO at Spacious (acquired by WeWork) and Marketing Manager at Google Cloud, with a background spanning healthcare, venture capital, and SaaS commercialization.

LinkedIn

Early access

Request a non-clinical evaluation unit.

We're placing a limited number of non-clinical IRIS units with interventional radiology teams ahead of our clinical pilot. Get hands-on, tell us what you think, and help shape the device.

  • 01
    A non-clinical IRIS unitFor hands-on bench and phantom evaluation with your team.
  • 02
    A walkthrough with our foundersSee the workflow, ask questions, and share what your suite needs.
  • 03
    Priority for the clinical pilotFirst consideration for pilot sites and early production units.

Evaluation units are for demonstration only and are not for use on patients.

Prefer email? Reach us at info@irisbiopsy.com

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